3BI7

Crystal structure of the SRA domain of E3 ubiquitin-protein ligase UHRF1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	E3 ubiquitin-protein ligase UHRF1	polymer	212	23910.2	1	UniProt (Q96T88) Pfam (PF02182) In PDB	Homo sapiens (human)	Ubiquitin-like PHD and RING finger domain-containing protein 1, Ubiquitin-like-containing PHD and RING finger domains protein 1, Inverted CCAAT box-binding protein of 90 kDa, Transcription factor ICBP90, Nuclear zinc finger protein Np95, Nuclear protein 95, HuNp95, RING finger protein 106
2	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
4	A	UNKNOWN LIGAND	non-polymer			1	Chemie (UNL)
5		water	water		18.0	209	Chemie (HOH)

Sequence modifications

A: 414 - 617 (UniProt: Q96T88)

PDB	External Database	Details
Mse 413	-	EXPRESSION TAG
Ala 618	-	EXPRESSION TAG
His 619	-	EXPRESSION TAG
His 620	-	EXPRESSION TAG
His 621	-	EXPRESSION TAG
His 622	-	EXPRESSION TAG
His 623	-	EXPRESSION TAG
His 624	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23910.2
Non-Polymers*	Number of molecules	6
	Total formula weight	344.3
All*	Total formula weight	24254.6

*Water molecules are not included.