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3BI7

Crystal structure of the SRA domain of E3 ubiquitin-protein ligase UHRF1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase UHRF1polymer21223910.21UniProt (Q96T88)
Pfam (PF02182)
Homo sapiens (human)Ubiquitin-like PHD and RING finger domain-containing protein 1, Ubiquitin-like-containing PHD and RING finger domains protein 1, Inverted CCAAT box-binding protein of 90 kDa, Transcription factor ICBP90, Nuclear zinc finger protein Np95, Nuclear protein 95, HuNp95, RING finger protein 106
2B
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
3C, D, E, F
(A)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
4G
(A)
UNKNOWN LIGANDnon-polymer1Chemie (UNL)
5H
(A)
waterwater18.0209Chemie (HOH)
Sequence modifications
A: 414 - 617 (UniProt: Q96T88)
PDBExternal DatabaseDetails
Mse 413-expression tag
Ala 618-expression tag
His 619-expression tag
His 620-expression tag
His 621-expression tag
His 622-expression tag
His 623-expression tag
His 624-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23910.2
Non-Polymers*Number of molecules6
Total formula weight344.3
All*Total formula weight24254.6
*Water molecules are not included.

242500

PDB entries from 2025-10-01

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