3BE1
Dual specific bH1 Fab in complex with the extracellular domain of HER2/ErbB-2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Receptor tyrosine-protein kinase erbB-2 | polymer | 624 | 68794.1 | 1 | UniProt (P04626) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) | Homo sapiens (human) | p185erbB2, C-erbB-2, NEU proto-oncogene, Tyrosine kinase-type cell surface receptor HER2, MLN 19, CD340 antigen |
2 | B (H) | Fab Fragment-Heavy Chain | polymer | 230 | 24557.5 | 1 | PDB (3BDY) | Homo sapiens (human) | |
3 | C (L) | Fab Fragment-Light Chain | polymer | 218 | 23956.6 | 1 | PDB (3BDY) | Homo sapiens (human) | |
4 | D, E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
5 | F (L) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 117308.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 637.7 | |
All* | Total formula weight | 117945.8 |