3BBP

Rab6-GTP:GCC185 Rab binding domain complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Ras-related protein Rab-6A	polymer	211	23853.1	3	UniProt (P20340) Pfam (PF00071)	Homo sapiens (human)	Rab-6
2	D, E, F (D, E, F)	GRIP and coiled-coil domain-containing protein 2	polymer	71	8153.3	3	UniProt (Q8IWJ2) Pfam (PF16704)	Homo sapiens (human)	Golgi coiled-coil protein GCC185, Ran-binding protein 2-like 4, RanBP2L4, CTCL tumor antigen se1-1, CLL-associated antigen KW-11, Renal carcinoma antigen NY-REN-53
3	G, I, K (A, B, C)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG) PubChem (888)
4	H, J, L (A, B, C)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	3	Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466)

Sequence modifications

A, B, C: 1 - 206 (UniProt: P20340)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag
Leu 72	Gln 72	engineered mutation
Leu 207	-	expression tag
Leu 208	-	expression tag

D, E, F: 1547 - 1612 (UniProt: Q8IWJ2)

PDB	External Database	Details
Gly 1542	-	expression tag
Pro 1543	-	expression tag
Leu 1544	-	expression tag
Gly 1545	-	expression tag
Ser 1546	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	96019.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1642.5
All*	Total formula weight	97661.6

*Water molecules are not included.