Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3BBP

Rab6-GTP:GCC185 Rab binding domain complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0002080	cellular_component	acrosomal membrane
A	0003924	molecular_function	GTPase activity
A	0003925	molecular_function	G protein activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0005802	cellular_component	trans-Golgi network
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006886	biological_process	intracellular protein transport
A	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
A	0006891	biological_process	intra-Golgi vesicle-mediated transport
A	0012505	cellular_component	endomembrane system
A	0016020	cellular_component	membrane
A	0018125	biological_process	peptidyl-cysteine methylation
A	0019882	biological_process	antigen processing and presentation
A	0019904	molecular_function	protein domain specific binding
A	0030667	cellular_component	secretory granule membrane
A	0031175	biological_process	neuron projection development
A	0031410	cellular_component	cytoplasmic vesicle
A	0031489	molecular_function	myosin V binding
A	0032588	cellular_component	trans-Golgi network membrane
A	0034067	biological_process	protein localization to Golgi apparatus
A	0034498	biological_process	early endosome to Golgi transport
A	0036064	cellular_component	ciliary basal body
A	0042147	biological_process	retrograde transport, endosome to Golgi
A	0070062	cellular_component	extracellular exosome
A	0070381	cellular_component	endosome to plasma membrane transport vesicle
A	0072385	biological_process	minus-end-directed organelle transport along microtubule
A	1903292	biological_process	protein localization to Golgi membrane
B	0000139	cellular_component	Golgi membrane
B	0002080	cellular_component	acrosomal membrane
B	0003924	molecular_function	GTPase activity
B	0003925	molecular_function	G protein activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005794	cellular_component	Golgi apparatus
B	0005802	cellular_component	trans-Golgi network
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006886	biological_process	intracellular protein transport
B	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
B	0006891	biological_process	intra-Golgi vesicle-mediated transport
B	0012505	cellular_component	endomembrane system
B	0016020	cellular_component	membrane
B	0018125	biological_process	peptidyl-cysteine methylation
B	0019882	biological_process	antigen processing and presentation
B	0019904	molecular_function	protein domain specific binding
B	0030667	cellular_component	secretory granule membrane
B	0031175	biological_process	neuron projection development
B	0031410	cellular_component	cytoplasmic vesicle
B	0031489	molecular_function	myosin V binding
B	0032588	cellular_component	trans-Golgi network membrane
B	0034067	biological_process	protein localization to Golgi apparatus
B	0034498	biological_process	early endosome to Golgi transport
B	0036064	cellular_component	ciliary basal body
B	0042147	biological_process	retrograde transport, endosome to Golgi
B	0070062	cellular_component	extracellular exosome
B	0070381	cellular_component	endosome to plasma membrane transport vesicle
B	0072385	biological_process	minus-end-directed organelle transport along microtubule
B	1903292	biological_process	protein localization to Golgi membrane
C	0000139	cellular_component	Golgi membrane
C	0002080	cellular_component	acrosomal membrane
C	0003924	molecular_function	GTPase activity
C	0003925	molecular_function	G protein activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0005794	cellular_component	Golgi apparatus
C	0005802	cellular_component	trans-Golgi network
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006886	biological_process	intracellular protein transport
C	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
C	0006891	biological_process	intra-Golgi vesicle-mediated transport
C	0012505	cellular_component	endomembrane system
C	0016020	cellular_component	membrane
C	0018125	biological_process	peptidyl-cysteine methylation
C	0019882	biological_process	antigen processing and presentation
C	0019904	molecular_function	protein domain specific binding
C	0030667	cellular_component	secretory granule membrane
C	0031175	biological_process	neuron projection development
C	0031410	cellular_component	cytoplasmic vesicle
C	0031489	molecular_function	myosin V binding
C	0032588	cellular_component	trans-Golgi network membrane
C	0034067	biological_process	protein localization to Golgi apparatus
C	0034498	biological_process	early endosome to Golgi transport
C	0036064	cellular_component	ciliary basal body
C	0042147	biological_process	retrograde transport, endosome to Golgi
C	0070062	cellular_component	extracellular exosome
C	0070381	cellular_component	endosome to plasma membrane transport vesicle
C	0072385	biological_process	minus-end-directed organelle transport along microtubule
C	1903292	biological_process	protein localization to Golgi membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 501

Chain	Residue
A	LYS26
A	THR27
A	THR45
A	ASP68
A	THR69
A	GTP500

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 501

Chain	Residue
B	ASP68
B	THR69
B	GTP500
B	LYS26
B	THR27
B	THR45

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 501

Chain	Residue
C	LYS26
C	THR27
C	THR45
C	ASP68
C	THR69
C	GTP500

site_id	AC4
Number of Residues	24
Details	BINDING SITE FOR RESIDUE GTP A 500

Chain	Residue
A	GLU21
A	GLN22
A	SER23
A	VAL24
A	GLY25
A	LYS26
A	THR27
A	SER28
A	PHE38
A	ASP39
A	ASN40
A	TYR42
A	GLN43
A	ALA44
A	THR45
A	GLY71
A	ASN126
A	LYS127
A	ASP129
A	LEU130
A	SER156
A	ALA157
A	LYS158
A	MG501

site_id	AC5
Number of Residues	24
Details	BINDING SITE FOR RESIDUE GTP B 500

Chain	Residue
B	GLU21
B	GLN22
B	SER23
B	VAL24
B	GLY25
B	LYS26
B	THR27
B	SER28
B	PHE38
B	ASP39
B	ASN40
B	TYR42
B	GLN43
B	ALA44
B	THR45
B	GLY71
B	ASN126
B	LYS127
B	ASP129
B	LEU130
B	SER156
B	ALA157
B	LYS158
B	MG501

site_id	AC6
Number of Residues	24
Details	BINDING SITE FOR RESIDUE GTP C 500

Chain	Residue
C	GLU21
C	GLN22
C	SER23
C	VAL24
C	GLY25
C	LYS26
C	THR27
C	SER28
C	PHE38
C	ASP39
C	ASN40
C	TYR42
C	GLN43
C	ALA44
C	THR45
C	GLY71
C	ASN126
C	LYS127
C	ASP129
C	LEU130
C	SER156
C	ALA157
C	LYS158
C	MG501

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	54
Details	Motif: {"description":"Switch 1","evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	57
Details	Motif: {"description":"Switch 2","evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	3
Details	Modified residue: {"description":"O-AMP-tyrosine; by Legionella DrrA","evidences":[{"source":"PubMed","id":"21822290","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	LEU72

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
B	LEU72

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
C	LEU72

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	SER23

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
B	SER23

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
C	SER23

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)