3BAH

Crystal structure of K112N mutant of Human acidic fibroblast growth factor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heparin-binding growth factor 1	polymer	146	16671.7	2	UniProt (P05230) Pfam (PF00167)	Homo sapiens (human)	HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta
2	C, D, E, F, G... (A, B)	FORMIC ACID	non-polymer		46.0	10	Chemie (FMT)
3	M, N (A, B)	water	water		18.0	276	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Asn 112	Lys 127	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33343.3
Non-Polymers*	Number of molecules	10
	Total formula weight	460.3
All*	Total formula weight	33803.6

*Water molecules are not included.