3BA9
Structural Basis for Inhbition of NAD-Dependent Ligase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA ligase | polymer | 332 | 38032.7 | 1 | UniProt (Q837V6) Pfam (PF01653) | Enterococcus faecalis (Streptococcus faecalis) | |
| 2 | B, C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F (A) | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | non-polymer | 335.2 | 1 | Chemie (NMN) | |||
| 4 | G (A) | N-[2-(2,4-diaminopyrido[2,3-d]pyrimidin-7-yl)-2-methylpropyl]-4-phenoxybenzamide | non-polymer | 428.5 | 1 | Chemie (3B9) | |||
| 5 | H, I, J (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | K (A) | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
A: 1 - 324 (UniProt: Q837V6)
| PDB | External Database | Details |
|---|---|---|
| Leu 325 | - | expression tag |
| Glu 326 | - | expression tag |
| His 327 | - | expression tag |
| His 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38032.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1424.2 | |
| All* | Total formula weight | 39456.9 |
