3BA0
Crystal structure of full-length human MMP-12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Macrophage metalloelastase | polymer | 365 | 42143.3 | 1 | UniProt (P39900) Pfam (PF00413) Pfam (PF00045) | Homo sapiens (Human) | HME, Matrix metalloproteinase-12, MMP-12, Macrophage elastase, ME |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E, F, G (A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | H (A) | ACETOHYDROXAMIC ACID | non-polymer | 75.1 | 1 | Chemie (HAE) | |||
| 5 | I (A) | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
A: 106 - 470 (UniProt: P39900)
| PDB | External Database | Details |
|---|---|---|
| Asp 171 | Phe 171 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42143.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 366.2 | |
| All* | Total formula weight | 42509.5 |
