3B9U

Crystal structure of L26N/D28N/H93G mutant of Human acidic fibroblast growth factor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Heparin-binding growth factor 1	polymer	146	16605.6	1	UniProt (P05230) Pfam (PF00167) In PDB	Homo sapiens (human)	HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta
2	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3		water	water		18.0	100	Chemie (HOH)

Sequence modifications

A: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Asn 26	Leu 41	engineered mutation
Asn 28	Asp 43	engineered mutation
Gly 93	His 108	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	16605.6
Non-Polymers*	Number of molecules	1
	Total formula weight	96.1
All*	Total formula weight	16701.7

*Water molecules are not included.