3B82
Structure of the eEF2-ExoA(E546H)-NAD+ complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | Elongation factor 2 | polymer | 842 | 93549.3 | 3 | UniProt (P32324) Pfam (PF00009) Pfam (PF03144) Pfam (PF14492) Pfam (PF03764) Pfam (PF00679) In PDB | Saccharomyces cerevisiae (Baker's yeast) | EF-2, Translation elongation factor 2, Eukaryotic elongation factor 2, eEF2, Ribosomal translocase |
| 2 | B, D, F | Exotoxin A | polymer | 207 | 22447.0 | 3 | UniProt (P11439) Pfam (PF09009) In PDB | Pseudomonas aeruginosa | NAD-dependent ADP-ribosyltransferase |
| 3 | B, D, F | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 3 | Chemie (NAD) | |||
| 4 | water | water | 18.0 | 548 | Chemie (HOH) |
Sequence modifications
B, D, F: 400 - 605 (UniProt: P11439)
| PDB | External Database | Details |
|---|---|---|
| Ala 399 | - | expression tag |
| Val 407 | Ile 432 | SEE REMARK 999 |
| Ser 515 | Gly 540 | SEE REMARK 999 |
| His 546 | Glu 571 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 347989.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1990.3 | |
| All* | Total formula weight | 349979.3 |
