3B80
HIV-1 protease mutant I54V complexed with gem-diol-amine intermediate NLLTQI
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10726.6 | 2 | UniProt (P04587) Pfam (PF00077) UniProt (by SIFTS) (Q7SSI0) | Human immunodeficiency virus type 1 BH10 | RETROPEPSIN |
| 2 | C (C) | peptide | polymer | 5 | 718.8 | 1 | PDB (3B7V) BIRD (PRD_000321) | Human immunodeficiency virus type 1 BH10 | |
| 3 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | E, F, G (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 5 | H, I, J (A, B, C) | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P04587)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 507 | engineered mutation |
| Ile 33 | Leu 533 | engineered mutation |
| Val 54 | Ile 554 | engineered mutation |
| Ile 63 | Leu 563 | engineered mutation |
| Ala 67 | Cys 567 | engineered mutation |
| Ala 95 | Cys 595 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 22172.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 129.3 | |
| All* | Total formula weight | 22301.5 |
