3B7W
Crystal structure of human acyl-CoA synthetase medium-chain family member 2A, with L64P mutation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor | polymer | 570 | 63334.6 | 1 | UniProt (Q08AH3) Pfam (PF00501) Pfam (PF13193) In PDB | Homo sapiens (human) | Acyl-CoA synthetase medium-chain family member 2A, Middle-chain acyl-CoA synthetase 2A, Butyrate-CoA ligase 2A, Butyryl coenzyme A synthetase 2A |
2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
3 | A | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 458 | Chemie (HOH) |
Sequence modifications
A: 32 - 577 (UniProt: Q08AH3)
PDB | External Database | Details |
---|---|---|
Met 8 | - | expression tag |
Gly 9 | - | expression tag |
His 10 | - | expression tag |
His 11 | - | expression tag |
His 12 | - | expression tag |
His 13 | - | expression tag |
His 14 | - | expression tag |
His 15 | - | expression tag |
Ser 16 | - | expression tag |
Ser 17 | - | expression tag |
Gly 18 | - | expression tag |
Val 19 | - | expression tag |
Asp 20 | - | expression tag |
Leu 21 | - | expression tag |
Gly 22 | - | expression tag |
Thr 23 | - | expression tag |
Glu 24 | - | expression tag |
Asn 25 | - | expression tag |
Leu 26 | - | expression tag |
Tyr 27 | - | expression tag |
Phe 28 | - | expression tag |
Gln 29 | - | expression tag |
Ser 30 | - | expression tag |
Met 31 | - | expression tag |
Pro 64 | Leu 64 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 63334.6 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 258.2 | |
All* | Total formula weight | 63592.8 |