3B6P

Structure of TREX1 in complex with a nucleotide and inhibitor ions (sodium and zinc)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Three prime repair exonuclease 1	polymer	247	27173.0	4	UniProt (Q91XB0)	Mus musculus (Mouse)	3'-5' exonuclease TREX1
2	E, H, K, N (A, B, C, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	F, I, L, O (A, B, C, D)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
4	G, J, M, P (A, B, C, D)	THYMIDINE-5'-PHOSPHATE	non-polymer		322.2	4	Chemie (TMP)
5	Q, R, S, T (A, B, C, D)	water	water		18.0	471	Chemie (HOH)

Sequence modifications

A, B, C, D: 9 - 245 (UniProt: Q91XB0)

PDB	External Database	Details
Met -1	-	expression tag
Lys 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
Pro 7	-	expression tag
Met 8	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	108692.0
Non-Polymers*	Number of molecules	12
	Total formula weight	1642.4
All*	Total formula weight	110334.5

*Water molecules are not included.