3B5B
Crystal structure of the thymidylate synthase k48q
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thymidylate synthase | polymer | 264 | 30514.6 | 2 | UniProt (P0A884) Pfam (PF00303) | Escherichia coli BL21 | TS, TSase |
| 2 | C (A) | 2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE | non-polymer | 355.2 | 1 | Chemie (NDU) | |||
| 3 | D, F (A, B) | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 4 | E (B) | 2'-DEOXY-5-NITROURIDINE 5'-(DIHYDROGEN PHOSPHATE) | non-polymer | 353.2 | 1 | Chemie (NDN) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 264 (UniProt: P0A884)
| PDB | External Database | Details |
|---|---|---|
| Gln 48 | Lys 48 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61029.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 800.4 | |
| All* | Total formula weight | 61829.6 |
