3B2W
Crystal structure of pyrimidine amide 11 bound to Lck
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase LCK | polymer | 277 | 32058.7 | 1 | UniProt (P06239) Pfam (PF07714) | Homo sapiens (human) | p56-LCK, Lymphocyte cell-specific protein-tyrosine kinase, LSK, T cell-specific protein-tyrosine kinase |
| 2 | B (A) | N-[5-({[2-fluoro-3-(trifluoromethyl)phenyl]amino}carbonyl)-2-methylphenyl]-4-methoxy-2-[(4-piperazin-1-ylphenyl)amino]pyrimidine-5-carboxamide | non-polymer | 623.6 | 1 | Chemie (9NH) | |||
| 3 | C (A) | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32058.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 623.6 | |
| All* | Total formula weight | 32682.3 |
