3B2T
Structure of phosphotransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fibroblast growth factor receptor 2 | polymer | 311 | 35650.1 | 2 | UniProt (P21802) Pfam (PF07714) | Homo sapiens (human) | FGFR-2, Keratinocyte growth factor receptor 2, CD332 antigen |
| 2 | C, D, F, G (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 3 | E, H (A, B) | 5'-O-[(S)-hydroxy{[(S)-hydroxy(methyl)phosphoryl]oxy}phosphoryl]adenosine | non-polymer | 425.2 | 2 | Chemie (M33) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 561 | Chemie (HOH) |
Sequence modifications
A, B: 458 - 768 (UniProt: P21802)
| PDB | External Database | Details |
|---|---|---|
| Thr 628 | Ala 628 | engineered mutation |
| Gln 767 | Glu 767 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71300.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1230.3 | |
| All* | Total formula weight | 72530.6 |
