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3B0W

Crystal structure of the orphan nuclear receptor ROR(gamma)t ligand-binding domain in complex with digoxin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Nuclear receptor ROR-gammapolymer24328307.82UniProt (P51449)
Pfam (PF00104)
Homo sapiens (human)Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, Retinoid-related orphan receptor-gamma
2C, D
(A, B)
DIGOXINnon-polymer780.92Chemie (DGX)
3E, F
(A, B)
waterwater18.073Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight56615.6
Non-Polymers*Number of molecules2
Total formula weight1561.9
All*Total formula weight58177.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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