3B0W
Crystal structure of the orphan nuclear receptor ROR(gamma)t ligand-binding domain in complex with digoxin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE DGX A 1 |
| Chain | Residue |
| A | HOH11 |
| A | PHE377 |
| A | LEU391 |
| A | CYS393 |
| A | LEU396 |
| A | HIS479 |
| A | HOH12 |
| A | GLU271 |
| A | LEU287 |
| A | CYS320 |
| A | ARG364 |
| A | MET365 |
| A | ARG367 |
| A | ALA368 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE DGX B 1 |
| Chain | Residue |
| B | HOH8 |
| B | HOH73 |
| B | GLU271 |
| B | GLN275 |
| B | LEU287 |
| B | CYS320 |
| B | ALA321 |
| B | MET365 |
| B | ARG367 |
| B | PHE377 |
| B | PHE388 |
| B | LEU391 |
| B | LEU396 |
| B | HIS479 |
