3AYC
Crystal structure of galectin-3 CRD domian complexed with GM1 pentasaccharide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Galectin-3 | polymer | 135 | 15409.7 | 2 | UniProt (P17931) Pfam (PF00337) In PDB | Homo sapiens (human) | Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen |
| 2 | C | beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 998.9 | 1 | In PDB GlyTouCan (G48558GR) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | A, B | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 6 | water | water | 18.0 | 442 | Chemie (HOH) |
Sequence modifications
A, B: 117 - 250 (UniProt: P17931)
| PDB | External Database | Details |
|---|---|---|
| Met 116 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30819.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 998.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 728.7 | |
| All* | Total formula weight | 32546.9 |
