3AV7

Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, KYN as substrates and KYA as products

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Putative uncharacterized protein PH0207	polymer	448	51162.9	2	UniProt (O57946) Pfam (PF00155) In PDB	Pyrococcus horikoshii	kynurneine aminotransferase
2	A, C	4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE	non-polymer		248.2	2	Chemie (PMP)
3	A, C	(2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid	non-polymer		208.2	2	Chemie (KYN)
4	A, C	4-hydroxyquinoline-2-carboxylic acid	non-polymer		189.2	2	Chemie (KYA)
5		water	water		18.0	555	Chemie (HOH)

Sequence modifications

A, C: 1 - 428 (UniProt: O57946)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	102325.8
Non-Polymers*	Number of molecules	6
	Total formula weight	1291.1
All*	Total formula weight	103616.9

*Water molecules are not included.