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3AQF

Crystal structure of the human CRLR/RAMP2 extracellular complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Receptor activity-modifying protein 2polymer9110581.51UniProt (O60895)
Pfam (PF04901)
Homo sapiens (human)Calcitonin-receptor-like receptor activity-modifying protein 2, CRLR activity-modifying protein 2
2B
(B)
Calcitonin gene-related peptide type 1 receptorpolymer12114035.91UniProt (Q16602)
Pfam (PF02793)
Homo sapiens (human)CGRP type 1 receptor, Calcitonin receptor-like receptor
3C, D
(A, B)
waterwater18.030Chemie (HOH)
Sequence modifications
A: 56 - 139 (UniProt: O60895)
PDBExternal DatabaseDetails
Gly 49-expression tag
Ser 50-expression tag
Ser 51-expression tag
Gly 52-expression tag
Ser 53-expression tag
Ser 54-expression tag
Gly 55-expression tag
B: 23 - 136 (UniProt: Q16602)
PDBExternal DatabaseDetails
Gly 16-expression tag
Ser 17-expression tag
Ser 18-expression tag
Gly 19-expression tag
Ser 20-expression tag
Ser 21-expression tag
Gly 22-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight24617.3
All*Total formula weight24617.3
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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