3APY

Properties and crystal structure of methylenetetrahydrofolate reductase from Thermus thermophilus HB8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Methylenetetrahydrofolate reductase	polymer	310	34648.7	8	UniProt (Q5SLG6) Pfam (PF02219)	Thermus thermophilus
2	I, K, L, M, O... (A, B, C, D, E...)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	8	Chemie (FAD)
3	J, N, P, R, T... (A, D, E, F, G...)	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
4	AA, BA, CA, DA, W... (E, F, G, H, A...)	water	water		18.0	909	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 296 (UniProt: Q5SLG6)

PDB	External Database	Details
Ala 297	-	expression tag
Lys 298	-	expression tag
Leu 299	-	expression tag
Ala 300	-	expression tag
Ala 301	-	expression tag
Ala 302	-	expression tag
Leu 303	-	expression tag
Glu 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	277189.4
Non-Polymers*	Number of molecules	14
	Total formula weight	6497.1
All*	Total formula weight	283686.6

*Water molecules are not included.