3APX

Crystal structure of the A variant of human alpha1-acid glycoprotein and chlorpromazine complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Alpha-1-acid glycoprotein 2	polymer	190	22691.3	1	UniProt (P19652) Pfam (PF00061) In PDB	Homo sapiens (human)	AGP 2, Orosomucoid-2, OMD 2
2	A	3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine	non-polymer		318.9	1	Chemie (Z80)
3	A	ACETIC ACID	non-polymer		60.1	1	Chemie (ACY)
4		water	water		18.0	138	Chemie (HOH)

Sequence modifications

A: 1 - 183 (UniProt: P19652)

PDB	External Database	Details
Met 0	-	expression tag
Arg 149	Cys 167	engineered mutation
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	22691.3
Non-Polymers*	Number of molecules	2
	Total formula weight	378.9
All*	Total formula weight	23070.2

*Water molecules are not included.