3APX
Crystal structure of the A variant of human alpha1-acid glycoprotein and chlorpromazine complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-1-acid glycoprotein 2 | polymer | 190 | 22691.3 | 1 | UniProt (P19652) Pfam (PF00061) | Homo sapiens (human) | AGP 2, Orosomucoid-2, OMD 2 |
| 2 | B (A) | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine | non-polymer | 318.9 | 1 | Chemie (Z80) | |||
| 3 | C (A) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 4 | D (A) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A: 1 - 183 (UniProt: P19652)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Arg 149 | Cys 167 | engineered mutation |
| His 184 | - | expression tag |
| His 185 | - | expression tag |
| His 186 | - | expression tag |
| His 187 | - | expression tag |
| His 188 | - | expression tag |
| His 189 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22691.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 378.9 | |
| All* | Total formula weight | 23070.2 |
