3AP2

Crystal structure of human tyrosylprotein sulfotransferase-2 complexed with PAP,C4 peptide, and phosphate ion

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein-tyrosine sulfotransferase 2	polymer	337	37743.7	2	UniProt (O60704) Pfam (PF13469)	Homo sapiens (human)	Tyrosylprotein sulfotransferase 2, TPST-2
2	C, D (S, T)	C4 peptide	polymer	9	1208.1	2
3	E, F (A, B)	ADENOSINE-3'-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (A3P)
4	G (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	H (T)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
6	I, J, K (A, B, S)	water	water		18.0	54	Chemie (HOH)

Sequence modifications

A, B: 43 - 359 (UniProt: O60704)

PDB	External Database	Details
Met 23	-	expression tag
Gly 24	-	expression tag
Ser 25	-	expression tag
Ser 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
Ser 33	-	expression tag
Ser 34	-	expression tag
Gly 35	-	expression tag
Val 36	-	expression tag
Pro 37	-	expression tag
Arg 38	-	expression tag
Gly 39	-	expression tag
Ser 40	-	expression tag
His 41	-	expression tag
Met 42	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	77903.6
Non-Polymers*	Number of molecules	4
	Total formula weight	1041.5
All*	Total formula weight	78945.1

*Water molecules are not included.