3ANT
Human soluble epoxide hydrolase in complex with a synthetic inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Epoxide hydrolase 2 | polymer | 336 | 38646.4 | 2 | UniProt (P34913) Pfam (PF00561) In PDB | Homo sapiens (human) | Soluble epoxide hydrolase, SEH, Epoxide hydratase, Cytosolic epoxide hydrolase, CEH |
2 | A, B | 4-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-N-[(1S,2R)-2-phenylcyclopropyl]piperidine-1-carboxamide | non-polymer | 354.4 | 2 | Chemie (S82) | |||
3 | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
A, B: 230 - 555 (UniProt: P34913)
PDB | External Database | Details |
---|---|---|
Met 220 | - | expression tag |
Lys 221 | - | expression tag |
Lys 222 | - | expression tag |
Gly 223 | - | expression tag |
His 224 | - | expression tag |
His 225 | - | expression tag |
His 226 | - | expression tag |
His 227 | - | expression tag |
His 228 | - | expression tag |
His 229 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 77292.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 708.9 | |
All* | Total formula weight | 78001.7 |