3ALO
Crystal structure of human non-phosphorylated MKK4 kinase domain ternary complex with AMP-PNP and p38 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity mitogen-activated protein kinase kinase 4 | polymer | 327 | 37471.0 | 1 | UniProt (P45985) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | B (E) | p38 peptide | polymer | 8 | 980.9 | 1 | Homo sapiens | ||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | E (A) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A: 80 - 399 (UniProt: P45985)
| PDB | External Database | Details |
|---|---|---|
| Met 79 | - | initiating methionine |
| His 400 | - | expression tag |
| His 401 | - | expression tag |
| His 402 | - | expression tag |
| His 403 | - | expression tag |
| His 404 | - | expression tag |
| His 405 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38451.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 530.5 | |
| All* | Total formula weight | 38982.4 |
