3ALN
Crystal Structure of human non-phosphorylated MKK4 kinase domain complexed with AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Dual specificity mitogen-activated protein kinase kinase 4 | polymer | 327 | 37471.0 | 3 | UniProt (P45985) Pfam (PF00069) | Homo sapiens (human) | MAP kinase kinase 4, MAPKK 4, MAPK/ERK kinase 4, MEK 4, JNK-activating kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, SAPK/ERK kinase 1, SEK1 |
| 2 | D, F, H (A, B, C) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 3 | Chemie (ANP) | |||
| 3 | E, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A, B, C: 80 - 399 (UniProt: P45985)
| PDB | External Database | Details |
|---|---|---|
| Met 79 | - | initiating methionine |
| His 400 | - | expression tag |
| His 401 | - | expression tag |
| His 402 | - | expression tag |
| His 403 | - | expression tag |
| His 404 | - | expression tag |
| His 405 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 112413.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1567.2 | |
| All* | Total formula weight | 113980.2 |
