3AL8

Plexin A2 / Semaphorin 6A complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Semaphorin-6A	polymer	556	62863.4	1	UniProt (O35464) Pfam (PF01403) Pfam (PF01437) In PDB	Mus musculus (mouse)	Semaphorin VIA, Sema VIA, Semaphorin-6A-1, SEMA6A-1, Semaphorin Q, Sema Q
2	B	Plexin-A2	polymer	539	60185.1	1	UniProt (P70207) Pfam (PF01403) Pfam (PF01437) In PDB	Mus musculus (mouse)	Plexin-2, Plex 2
3	C, D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	E	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1235.1	1	In PDB GlyTouCan (G55220VL)
5	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A: 19 - 570 (UniProt: O35464)

PDB	External Database	Details
Gly 15	-	expression tag
Ser 16	-	expression tag
Ser 17	-	expression tag
Arg 18	-	expression tag

B: 31 - 561 (UniProt: P70207)

PDB	External Database	Details
Ser 562	-	expression tag
Arg 563	-	expression tag
Glu 564	-	expression tag
Asn 565	-	expression tag
Leu 566	-	expression tag
Tyr 567	-	expression tag
Phe 568	-	expression tag
Gln 569	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	123048.5
Branched	Number of molecules	3
	Total formula weight	2083.9
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	125796.0

*Water molecules are not included.