3AHQ

hyperactive human Ero1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	ERO1-like protein alpha	polymer	465	54172.8	1	UniProt (Q96HE7) Pfam (PF04137)	Homo sapiens (human)	ERO1-L-alpha, ERO1-L, Oxidoreductin-1-L-alpha, Endoplasmic oxidoreductin-1-like protein
2	B (A)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	1	Chemie (FAD)
3	C (A)	water	water		18.0	65	Chemie (HOH)

Sequence modifications

A: 22 - 468 (UniProt: Q96HE7)

PDB	External Database	Details
Met 4	-	expression tag
Gly 5	-	expression tag
Ser 6	-	expression tag
Ser 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
Ser 14	-	expression tag
Ser 15	-	expression tag
Gly 16	-	expression tag
His 17	-	expression tag
Ile 18	-	expression tag
Glu 19	-	expression tag
Gly 20	-	expression tag
Arg 21	-	expression tag
Ala 104	Cys 104	engineered mutation
Ala 131	Cys 131	engineered mutation
Ala 166	Cys 166	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	54172.8
Non-Polymers*	Number of molecules	1
	Total formula weight	785.5
All*	Total formula weight	54958.4

*Water molecules are not included.