3AEM
Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 containing Michaelis complex and methionine imine-pyridoxamine-5'-phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D | Methionine gamma-lyase | polymer | 389 | 42350.8 | 3 | UniProt (Q86D28) Pfam (PF01053) In PDB | Entamoeba histolytica | |
| 2 | C | Methionine gamma-lyase | polymer | 389 | 42578.9 | 1 | UniProt (Q86D28) Pfam (PF01053) In PDB | Entamoeba histolytica | |
| 3 | A, B, D | (2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-4-(methylsulfanyl)butanoic acid | non-polymer | 378.3 | 3 | Chemie (2LM) | |||
| 4 | A, B, C, D | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | A, C | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | C | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) | |||
| 7 | water | water | 18.0 | 890 | Chemie (HOH) |
Sequence modifications
A, B, D: 1 - 389 (UniProt: Q86D28)
C: 1001 - 1389 (UniProt: Q86D28)
| PDB | External Database | Details |
|---|---|---|
| Leu 308 | Ser 308 | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Leu 1308 | Ser 308 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 169631.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1852.7 | |
| All* | Total formula weight | 171483.9 |
