3AE0
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with geranylgeranyl thiopyrophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dehydrosqualene synthase | polymer | 293 | 34711.4 | 2 | UniProt (A9JQL9) Pfam (PF00494) | Staphylococcus aureus | Diapophytoene synthase, 4,4'-diapophytoene synthase, DAP synthase |
| 2 | C, D, H, I (A, B) | phosphonooxy-[(10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]sulfanyl-phosphinic acid | non-polymer | 466.5 | 4 | Chemie (GGS) | |||
| 3 | E, F, G, J, K... (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 4 | M, N (A, B) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 287 (UniProt: A9JQL9)
| PDB | External Database | Details |
|---|---|---|
| Ala -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ala 26 | Phe 26 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69422.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2011.9 | |
| All* | Total formula weight | 71434.7 |
