3ABD

Structure of human REV7 in complex with a human REV3 fragment in a monoclinic crystal

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, B)	Mitotic spindle assembly checkpoint protein MAD2B	polymer	227	26101.2	2	UniProt (Q9UI95) Pfam (PF02301)	Homo sapiens (human)	REV7, MAD2-like 2, hREV7
2	B, D (X, Y)	DNA polymerase zeta catalytic subunit	polymer	52	5632.3	2	UniProt (O60673)	Homo sapiens (human)	REV3, hREV3
3	E, F, G, H (A, X, B, Y)	water	water		18.0	257	Chemie (HOH)

Sequence modifications

A, B: 1 - 211 (UniProt: Q9UI95)

PDB	External Database	Details
Met -15	-	initiating methionine
Gly -14	-	expression tag
Ser -13	-	expression tag
Ser -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Ser -5	-	expression tag
Gln -4	-	expression tag
Asp -3	-	expression tag
Pro -2	-	expression tag
Asn -1	-	expression tag
Ser 0	-	expression tag
Ala 124	Arg 124	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	63467.1
All*	Total formula weight	63467.1

*Water molecules are not included.