3A7Q

Structural basis for specific recognition of reelin by its receptors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Reelin	polymer	725	81317.1	1	UniProt (Q60841) Pfam (PF21471)	Mus musculus (mouse)	Reeler protein
2	B (B)	Low-density lipoprotein receptor-related protein 8	polymer	44	5082.4	1	UniProt (Q14114) Pfam (PF00057)	Homo sapiens (human)	Apolipoprotein E receptor 2
3	C (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	D, E, F (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
5	G, H, I, J, L (A, B)	CALCIUM ION	non-polymer		40.1	5	Chemie (CA)
6	K (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
7	M, N (A, B)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

A: 1948 - 2661 (UniProt: Q60841)

PDB	External Database	Details
Gly 1946	-	expression tag
Arg 1947	-	expression tag
Ala 2101	Cys 2101	engineered mutation
Ser 2662	-	expression tag
Arg 2663	-	expression tag
Leu 2664	-	expression tag
Glu 2665	-	expression tag
Asn 2666	-	expression tag
Leu 2667	-	expression tag
Tyr 2668	-	expression tag
Phe 2669	-	expression tag
Gln 2670	-	expression tag

B: 42 - 83 (UniProt: Q14114)

PDB	External Database	Details
Gly 40	-	expression tag
Ser 41	-	expression tag
Glu 46	Asp 46	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	86399.5
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	9
	Total formula weight	929.4
All*	Total formula weight	87753.3

*Water molecules are not included.