34CY

Homo sapiens Eukaryotic translation initiation factor 4E (eIF4E) in complex with synthetic mRNA cap analogs

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Eukaryotic translation initiation factor 4E	polymer	193	22444.5	4	UniProt (P06730)	Homo sapiens (human)	eIF-4E,eIF4E,eIF-4F 25 kDa subunit,mRNA cap-binding protein
2	E, F, G, H (A, B, C, D)	[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-2-[[[[[(1~{R},3~{R},4~{R},7~{S})-3-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-yl)-7-oxidanyl-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-4-methylsulfanyl-oxolan-3-yl] (2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)methyl hydrogen phosphate	non-polymer		1072.7	4	Chemie (A1KUD)
3	I, J, K, L (A, B, C, D)	water	water		18.0	204	Chemie (HOH)

Sequence modifications

A, B, C, D: 28 - 217 (UniProt: P06730)

PDB	External Database	Details
Gly 25	-	expression tag
Pro 26	-	expression tag
Met 27	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	89778.0
Non-Polymers*	Number of molecules	4
	Total formula weight	4290.6
All*	Total formula weight	94068.7

*Water molecules are not included.