32QP

Human TRIM21 PRYSPRY domain in complex with PRLX-93936

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	E3 ubiquitin-protein ligase TRIM21	polymer	202	23022.8	1	UniProt (P19474)	Homo sapiens (human)	52 kDa Ro protein,52 kDa ribonucleoprotein autoantigen Ro/SS-A,RING finger protein 81,Ro(SS-A),Sjoegren syndrome type A antigen,SS-A,Tripartite motif-containing protein 21
2	B (A)	3-(2-ethoxyphenyl)-2-(piperazin-1-ylmethyl)quinazolin-4-one	non-polymer		364.4	1	Chemie (A1KEH)
3	C (A)	water	water		18.0	44	Chemie (HOH)

Sequence modifications

A: 287 - 465 (UniProt: P19474)

PDB	External Database	Details
Met 264	-	initiating methionine
His 265	-	expression tag
His 266	-	expression tag
His 267	-	expression tag
His 268	-	expression tag
His 269	-	expression tag
His 270	-	expression tag
Ser 271	-	expression tag
Ser 272	-	expression tag
Gly 273	-	expression tag
Val 274	-	expression tag
Asp 275	-	expression tag
Leu 276	-	expression tag
Gly 277	-	expression tag
Thr 278	-	expression tag
Glu 279	-	expression tag
Asn 280	-	expression tag
Leu 281	-	expression tag
Tyr 282	-	expression tag
Phe 283	-	expression tag
Gln 284	-	expression tag
Ser 285	-	expression tag
Met 286	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23022.8
Non-Polymers*	Number of molecules	1
	Total formula weight	364.4
All*	Total formula weight	23387.3

*Water molecules are not included.