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32JN

Structure of the pathogenic variant P157S of Human SHMT2 in the apo open dimeric conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine hydroxymethyltransferase, mitochondrialpolymer48653799.11UniProt (P34897)Homo sapiens (human)SHMT,Glycine hydroxymethyltransferase,Serine methylase
2B
(A)
waterwater18.039Chemie (HOH)
Sequence modifications
A: 22 - 504 (UniProt: P34897)
PDBExternal DatabaseDetails
Gly 19-expression tag
Ser 20-expression tag
His 21-expression tag
Ser 157Pro 157variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight53799.1
All*Total formula weight53799.1
*Water molecules are not included.

259015

PDB entries from 2026-09-02

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