31AK

Structure of native human leukocyte myeloperoxidase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, E)	Myeloperoxidase light chain	polymer	114	12894.5	2	UniProt (P05164)	Homo sapiens (human)
2	B, D (B, F)	Myeloperoxidase	polymer	467	53305.3	2	UniProt (P05164)	Homo sapiens (human)	MPO
3	E, H (C, H)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	2	In PDB GlyTouCan (G56014GC)
4	F, I (D, I)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
5	G (G)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1057.0	1	In PDB GlyTouCan (G82348BZ)
6	J (J)	alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1219.1	1	In PDB GlyTouCan (G27389SR)
7	K, M, Q, T (A, B, E, F)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL) PubChem (312)
8	L, S (B, F)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA) PubChem (271)
9	N, R (B, E)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
10	O, P, U, V (B, F)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG) PubChem (24139)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	132399.5
Branched	Number of molecules	6
	Total formula weight	5595.1
Non-Polymers*	Number of molecules	12
	Total formula weight	2339.8
All*	Total formula weight	140334.3

*Water molecules are not included.