316D
Selectivity of F8-actinomycin D for RNA:DNA hybrids and its anti-leukemia activity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3') | polymer | 8 | 2426.6 | 2 | |||
| 2 | C (C) | 8-FLUORO-ACTINOMYCIN D | polymer | 11 | 1309.4 | 1 | NOR (NOR00228) BIRD (PRD_000006) | STREPTOMYCES ANTIBIOTICUS | DACTINOMYCIN |
Sequence modifications
C: 1 - 11 (NOR: NOR00228)
| PDB | External Database | Details |
|---|---|---|
| Pxf 6 | Pxz 6 | chromophore |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 6162.7 | |
| All* | Total formula weight | 6162.7 |
