30TT
14-3-3sigma protein binding to TSC2-wt peptide and molecular glue 22
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (P) | TSC2 peptide pS1254 | polymer | 7 | 781.8 | 1 | Homo sapiens | ||
| 3 | C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 4 | E (A) | ~{N}-[[1-(4-bromophenyl)sulfonylpiperidin-4-yl]methyl]-2-chloranyl-ethanamide | non-polymer | 409.7 | 1 | Chemie (WPN) PubChem (176404572) | |||
| 5 | F, G, H, I (A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) PubChem (271) | |||
| 6 | J, K (A, P) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27324.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 640.9 | |
| All* | Total formula weight | 27965.7 |
