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2ZZP

The crystal structure of human Atg4B(C74S)- LC3(1-124) complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cysteine protease ATG4Bpolymer35740162.61UniProt (Q9Y4P1)
Pfam (PF03416)
Homo sapiens (human)HsAtg4B, Autophagy-related protein 4 homolog B, hAPG4B, Autophagin-1, Autophagy-related cysteine endopeptidase 1, AUT-like 1 cysteine endopeptidase
2B
(B)
Microtubule-associated proteins 1A/1B light chain 3Bpolymer12914932.11UniProt (Q62625)
Pfam (PF02991)
Rattus norvegicus (rat)Microtubule-associated protein 1 light chain 3 beta, MAP1A/1B light chain 3 B, MAP1A/MAP1B LC3 B, MAP1 light chain 3-like protein 2, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B
3C, D
(A, B)
waterwater18.0153Chemie (HOH)
Sequence modifications
A: 1 - 354 (UniProt: Q9Y4P1)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Ser 74Cys 74engineered mutation
B: 1 - 124 (UniProt: Q62625)
PDBExternal DatabaseDetails
Gly -4-expression tag
Pro -3-expression tag
Leu -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight55094.8
All*Total formula weight55094.8
*Water molecules are not included.

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PDB entries from 2024-10-30

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