2ZZ7
Orotidine Monophosphate Decarboxylase K72A mutant complexed with BMP (produced from 6-Iodo-UMP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Orotidine 5'-phosphate decarboxylase | polymer | 252 | 27321.3 | 1 | UniProt (O26232) Pfam (PF00215) | Methanothermobacter thermautotrophicus | OMP DECARBOXYLASE, OMPDCASE, OMPDECASE |
| 2 | B (A) | 6-HYDROXYURIDINE-5'-PHOSPHATE | non-polymer | 340.2 | 1 | Chemie (BMP) | |||
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (A) | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A: 1 - 228 (UniProt: O26232)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 72 | Lys 72 | engineered mutation |
| Pro 101 | Arg 101 | SEE REMARK 999 |
| Arg 226 | Leu 226 | engineered mutation |
| Ile 227 | Asn 227 | engineered mutation |
| Glu 229 | - | expression tag |
| Asp 230 | - | expression tag |
| Pro 231 | - | expression tag |
| Ala 232 | - | expression tag |
| Ala 233 | - | expression tag |
| Asn 234 | - | expression tag |
| Lys 235 | - | expression tag |
| Ala 236 | - | expression tag |
| Arg 237 | - | expression tag |
| Lys 238 | - | expression tag |
| Glu 239 | - | expression tag |
| Ala 240 | - | expression tag |
| Glu 241 | - | expression tag |
| Leu 242 | - | expression tag |
| Ala 243 | - | expression tag |
| Ala 244 | - | expression tag |
| Ala 245 | - | expression tag |
| Thr 246 | - | expression tag |
| Ala 247 | - | expression tag |
| Glu 248 | - | expression tag |
| Gln 249 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27321.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 524.4 | |
| All* | Total formula weight | 27845.7 |
