2ZWL
Human factor viia-tissue factor complexed with highly selective peptide inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L | Factor VII light chain | polymer | 152 | 17487.1 | 1 | UniProt (P08709) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) In PDB | Homo sapiens (Human) | Serum prothrombin conversion accelerator, SPCA, Proconvertin, eptacog alfa |
2 | H | Factor VII heavy chain | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) In PDB | Homo sapiens (Human) | Serum prothrombin conversion accelerator, SPCA, Proconvertin, eptacog alfa |
3 | T | Tissue factor | polymer | 218 | 24697.4 | 1 | UniProt (P13726) Pfam (PF01108) Pfam (PF09294) In PDB | Homo sapiens (Human) | TF, Coagulation factor III, Thromboplastin, CD142 antigen |
4 | L | beta-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (BGC) | |||
5 | L | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
6 | L, H | CALCIUM ION | non-polymer | 40.1 | 9 | Chemie (CA) | |||
7 | H | 2-[[(2R)-1-[[(2S)-5-amino-1-[(4-carbamimidoylphenyl)methylamino]-1,5-dioxo-pentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxo-propan-2-yl]sulfamoyl]ethanoic acid | non-polymer | 585.6 | 1 | Chemie (567) | |||
8 | water | water | 18.0 | 404 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 70287.7 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1290.6 | |
All* | Total formula weight | 71578.4 |