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2ZWL

Human factor viia-tissue factor complexed with highly selective peptide inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
Factor VII light chainpolymer15217487.11UniProt (P08709)
Pfam (PF00594)
Pfam (PF00008)
Pfam (PF14670)
Homo sapiens (Human)Serum prothrombin conversion accelerator, SPCA, Proconvertin, eptacog alfa
2B
(H)
Factor VII heavy chainpolymer25428103.31UniProt (P08709)
Pfam (PF00089)
Homo sapiens (Human)Serum prothrombin conversion accelerator, SPCA, Proconvertin, eptacog alfa
3C
(T)
Tissue factorpolymer21824697.41UniProt (P13726)
Pfam (PF01108)
Pfam (PF09294)
Homo sapiens (Human)TF, Coagulation factor III, Thromboplastin, CD142 antigen
4D
(L)
beta-D-glucopyranosenon-polymer180.21Chemie (BGC)
5E
(L)
alpha-L-fucopyranosenon-polymer164.21Chemie (FUC)
6F, G, H, I, J...
(L, H)
CALCIUM IONnon-polymer40.19Chemie (CA)
7N
(H)
2-[[(2R)-1-[[(2S)-5-amino-1-[(4-carbamimidoylphenyl)methylamino]-1,5-dioxo-pentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxo-propan-2-yl]sulfamoyl]ethanoic acidnon-polymer585.61Chemie (567)
8P, Q, R
(L, H, T)
waterwater18.0404Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight70287.7
Non-Polymers*Number of molecules12
Total formula weight1290.6
All*Total formula weight71578.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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