2ZVO

NEMO CoZi domain in complex with diubiquitin in C2 space group

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, G)	UBC protein	polymer	154	17279.8	2	UniProt (Q96C32) Pfam (PF00240) UniProt (by SIFTS) (P0CG48)	Homo sapiens (human)
2	C, D (B, D)	NF-kappa-B essential modulator	polymer	92	10676.1	2	UniProt (O88522) Pfam (PF16516)	Mus musculus (mouse)	NEMO, NF-kappa-B essential modifier, Inhibitor of nuclear factor kappa-B kinase subunit gamma, IkB kinase subunit gamma, I-kappa-B kinase gamma, IKK-gamma, IKKG, IkB kinase-associated protein 1, IKKAP1, mFIP-3
3	E, F, G, H (A, G, B, D)	water	water		18.0	174	Chemie (HOH)

Sequence modifications

A, G: 1 - 152 (UniProt: Q96C32)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag

B, D: 250 - 339 (UniProt: O88522)

PDB	External Database	Details
Gly 248	-	expression tag
Ser 249	-	expression tag
Ala 282	Glu 282	engineered mutation
Ala 285	Lys 285	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	55911.9
All*	Total formula weight	55911.9

*Water molecules are not included.