2ZTW
Structure of 3-isopropylmalate dehydrogenase in complex with the inhibitor and NAD+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3-isopropylmalate dehydrogenase | polymer | 345 | 36825.2 | 1 | UniProt (Q5SIY4) Pfam (PF00180) | Thermus thermophilus | Beta-IPM dehydrogenase, IMDH, 3-IPM-DH |
| 2 | B (A) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 3 | C (A) | (2Z)-2-hydroxy-3-(methylsulfanyl)prop-2-enoic acid | non-polymer | 134.2 | 1 | Chemie (DEI) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36825.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 821.9 | |
| All* | Total formula weight | 37647.0 |
