2ZS1

Structural Basis for the Heterotropic and Homotropic Interactions of Invertebrate Giant Hemoglobin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Extracellular giant hemoglobin major globin subunit A1	polymer	140	15188.9	1	UniProt (Q7M419) Pfam (PF00042) In PDB	Oligobrachia mashikoi (Beard worm)	Major globin chain b
2	B	Extracellular giant hemoglobin major globin subunit A2	polymer	142	15327.1	1	UniProt (Q7M413) Pfam (PF00042) In PDB	Oligobrachia mashikoi (Beard worm)	Major globin chain a5
3	C	Extracellular giant hemoglobin major globin subunit B2	polymer	147	15621.3	1	UniProt (Q7M418) Pfam (PF00042) In PDB	Oligobrachia mashikoi (Beard worm)	Major globin chain c
4	D	Extracellular giant hemoglobin major globin subunit B1	polymer	145	14693.3	1	UniProt (Q5KSB7) Pfam (PF00042) In PDB	Oligobrachia mashikoi (Beard worm)	Major globin chain d
5	A, B, C, D	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	4	Chemie (HEM)
6	A, B, C, D	OXYGEN MOLECULE	non-polymer		32.0	4	Chemie (OXY)
7	A, D	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
8	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
9	B	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
10		water	water		18.0	643	Chemie (HOH)

Sequence modifications

D: 1 - 145 (UniProt: Q5KSB7)

PDB	External Database	Details
Ile 31	Val 47	microheterogeneity
Val 38	Ala 54	microheterogeneity
Thr 41	Ala 57	microheterogeneity
Ser 57	Asn 73	microheterogeneity
Ser 58	Asn 74	microheterogeneity
Ala 59	Pro 75	microheterogeneity
Ile 69	Val 85	microheterogeneity
Lys 97	Arg 113	microheterogeneity
Glu 112	Gln 128	microheterogeneity
Gly 131	Glu 147	microheterogeneity

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	60830.6
Non-Polymers*	Number of molecules	16
	Total formula weight	3206.3
All*	Total formula weight	64036.9

*Water molecules are not included.