2ZQD
Ceftazidime acyl-intermediate structure of class a beta-lact Toho-1 E166A/R274N/R276N triple mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase Toho-1 | polymer | 262 | 28117.8 | 1 | UniProt (Q47066) Pfam (PF00144) Pfam (PF00905) Pfam (PF13354) | Escherichia coli | |
| 2 | B, C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F (A) | ACYLATED CEFTAZIDIME | non-polymer | 469.5 | 1 | Chemie (CAZ) | |||
| 4 | G (A) | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence modifications
A: 26 - 290 (UniProt: Q47066)
| PDB | External Database | Details |
|---|---|---|
| Ala 166 | Glu 169 | engineered mutation |
| Asn 274 | Arg 275 | engineered mutation |
| Asn 276 | Arg 277 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28117.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 853.7 | |
| All* | Total formula weight | 28971.5 |
