2ZP1

Structual basis of iodo-tyrosine recognition by engineered archeal tyrosyl-tRNA synthetase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tyrosyl-tRNA synthetase	polymer	314	36114.9	1	UniProt (Q57834) Pfam (PF00579) In PDB	Methanocaldococcus jannaschii (Methanococcus jannaschii)	Tyrosine-tRNA ligase, TyrRS
2	A	3-IODO-TYROSINE	non-polymer		307.1	1	Chemie (IYR)
3		water	water		18.0	280	Chemie (HOH)

Sequence modifications

A: 1 - 306 (UniProt: Q57834)

PDB	External Database	Details
Ala 70	His 70	engineered mutation
Thr 158	Asp 158	engineered mutation
Ser 159	Ile 159	engineered mutation
Tyr 286	Asp 286	engineered mutation
Leu 307	-	expression tag
Glu 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag
His 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36114.9
Non-Polymers*	Number of molecules	1
	Total formula weight	307.1
All*	Total formula weight	36422.0

*Water molecules are not included.