2ZOL

Crystal structure of H-2Db in complex with the W513S variant of JHMV epitope S510

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, C)	H-2 class I histocompatibility antigen, D-B alpha chain	polymer	278	32463.1	2	UniProt (P01899) Pfam (PF00129) Pfam (PF07654)	Mus musculus (mouse)	H-2D(B)
2	C, D (D, B)	Beta-2-microglobulin	polymer	100	11835.6	2	UniProt (P01887) Pfam (PF07654)	Mus musculus (mouse)
3	E, F (F, E)	9-meric peptide from Spike glycoprotein	polymer	9	910.0	2	UniProt (Q02385)		peptidic epitope S510
4	G (F)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5	H, I, J, K, L... (A, C, D, B, F...)	water	water		18.0	116	Chemie (HOH)

Sequence modifications

A, C: 1 - 275 (UniProt: P01899)

PDB	External Database	Details
Arg 276	-	expression tag
Trp 277	-	expression tag
Glu 278	-	expression tag

D, B: 1 - 99 (UniProt: P01887)

PDB	External Database	Details
Met 0	-	initiating methionine

F, E: 1 - 9 (UniProt: Q02385)

PDB	External Database	Details
Aba 1	Cys 510	modified residue
Ser 4	Trp 513	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	90417.3
Non-Polymers*	Number of molecules	1
	Total formula weight	96.1
All*	Total formula weight	90513.4

*Water molecules are not included.