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2ZNQ

Human PPAR delta ligand binding domain in complex with a synthetic agonist TIPP401

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BPeroxisome proliferator-activated receptor deltapolymer27631527.62UniProt (Q03181)
Pfam (PF00104)
In PDB
Homo sapiens (human)PPAR-delta, PPAR-beta, Nuclear receptor subfamily 1 group C member 2, Nuclear hormone receptor 1, NUC1, NUCI
2A, Bheptyl beta-D-glucopyranosidenon-polymer278.32Chemie (B7G)
3A, B(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acidnon-polymer427.42Chemie (401)
4waterwater18.083Chemie (HOH)
Sequence modifications
A, B: 206 - 477 (UniProt: Q03181)
PDBExternal DatabaseDetails
Gly 202-expression tag
Ser 203-expression tag
His 204-expression tag
Met 205-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight63055.3
Non-Polymers*Number of molecules4
Total formula weight1411.5
All*Total formula weight64466.8
*Water molecules are not included.

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PDB entries from 2024-03-27

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