2ZNQ
Human PPAR delta ligand binding domain in complex with a synthetic agonist TIPP401
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor delta | polymer | 276 | 31527.6 | 2 | UniProt (Q03181) Pfam (PF00104) | Homo sapiens (human) | PPAR-delta, PPAR-beta, Nuclear receptor subfamily 1 group C member 2, Nuclear hormone receptor 1, NUC1, NUCI |
| 2 | C, E (A, B) | heptyl beta-D-glucopyranoside | non-polymer | 278.3 | 2 | Chemie (B7G) | |||
| 3 | D, F (A, B) | (2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid | non-polymer | 427.4 | 2 | Chemie (401) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A, B: 206 - 477 (UniProt: Q03181)
| PDB | External Database | Details |
|---|---|---|
| Gly 202 | - | expression tag |
| Ser 203 | - | expression tag |
| His 204 | - | expression tag |
| Met 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63055.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1411.5 | |
| All* | Total formula weight | 64466.8 |
