2ZNQ
Human PPAR delta ligand binding domain in complex with a synthetic agonist TIPP401
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peroxisome proliferator-activated receptor delta | polymer | 276 | 31527.6 | 2 | UniProt (Q03181) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-delta, PPAR-beta, Nuclear receptor subfamily 1 group C member 2, Nuclear hormone receptor 1, NUC1, NUCI |
2 | A, B | heptyl beta-D-glucopyranoside | non-polymer | 278.3 | 2 | Chemie (B7G) | |||
3 | A, B | (2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid | non-polymer | 427.4 | 2 | Chemie (401) | |||
4 | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A, B: 206 - 477 (UniProt: Q03181)
PDB | External Database | Details |
---|---|---|
Gly 202 | - | expression tag |
Ser 203 | - | expression tag |
His 204 | - | expression tag |
Met 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 63055.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1411.5 | |
All* | Total formula weight | 64466.8 |