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2ZN7

CRYSTAL STRUCTURES OF PTP1B-Inhibitor Complexes

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 1polymer29934833.71UniProt (P18031)
Pfam (PF00102)
Homo sapiens (Human)Protein-tyrosine phosphatase 1B, PTP-1B
2B
(A)
4-bromo-3-(carboxymethoxy)-5-{3-[cyclohexyl(phenylcarbonyl)amino]phenyl}thiophene-2-carboxylic acidnon-polymer558.41Chemie (410)
3C
(A)
waterwater18.0218Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34833.7
Non-Polymers*Number of molecules1
Total formula weight558.4
All*Total formula weight35392.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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