2ZKS

Structural insights into the proteolytic machinery of apoptosis-inducing Granzyme M

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Granzyme M	polymer	240	26132.5	1	UniProt (P51124) Pfam (PF00089) In PDB	Homo sapiens (Human)	Met-ase, Natural killer cell granular protease, HU-Met-1, Met-1 serine protease
2	C	hGzmM inhibitor	polymer	6	515.1	1
3	A	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
4		water	water		18.0	83	Chemie (HOH)

Sequence modifications

A: 1 - 232 (UniProt: P51124)

PDB	External Database	Details
Leu 233	-	expression tag
Glu 234	-	expression tag
His 235	-	expression tag
His 236	-	expression tag
His 237	-	expression tag
His 238	-	expression tag
His 239	-	expression tag
His 240	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	26647.7
Non-Polymers*	Number of molecules	4
	Total formula weight	384.3
All*	Total formula weight	27031.9

*Water molecules are not included.